Redstone family say CBS plan 'invalid' as courtroom showdown looms
The board of CBS Corp headed to court on Wednesday in an attempt to strip voting control from the Redstone family, which has sought to merge one of the biggest U.S. media companies with peer Viacom Inc.
CRISPR-Cas9, the gene-snipping technology that has been heralded as a potential way to treat cancer and other genetic diseases, may present more risks than originally thought.
According to a new study released today in Nature Biotechnology, the DNA editing technique has been shown to produce unintended genomic consequences. The study–which was in review for over a year, according to STAT–found that when CRISPR edited specific genes, it also impacted unrelated genes that were far removed from the pair targets. Essentially, this means that CRISPR could unknowingly delete or alter non-targeted genes, which could lead to myriad unintended consequences. This is especially frightening, since the technology is going to be used in human clinical trials.
Meanwhile, other scientists working with CRISPR are trying to downplay the findings, telling STAT that there have been no reported adverse effects similar to what the study describes. The news, however, has brought about a market reaction–at least three publicly traded companies that focus on CRISPR-based therapies are in stock nosedive. Crispr Therapeutics is down by over 6%; Editas fell by over 3%; and Intellia Therapeutics dropped by over 5%.
The author of the paper told STAT that these findings should be seen as a “wake-up call” and that the potential genetic consequences CRISPR may bring have been “serious underestimated.”
At the very least, this paper points to the need to look closer at the impact CRISPR could have on patients. It’s true that it may help cure some diseases. Yet an unintended gene deletion could also lead to other unknown maladies. You can read the full STAT write-up here.
Shervin Pishevar has been in quite the giving mood.
Last night, the controversial VC and Hyperloop One cofounder tweeted, “How can I help you?”–and it appears to be a genuine questions for his 91,000+ followers. Pishevar has been entertaining requests for job referrals, project funding, and help with student loans.
“Was inspired to start #howcanhelpyou movement,” Pishevar wrote. “If we all ask ‘How Can I Help You?’ we will start a wave of goodness that spreads everywhere. I will try help solve any problems people have because it’s a good thing to do. How can I help YOU?”
This also means if you have trouble getting food on the table or pay for school supplies or tuition or pay for rent send me your problem. Just ask me. I will try help. #howcanihelp https://t.co/7tc4jpvmZS
— Shervin Pishevar (@shervin) July 13, 2018
Pishevar’s public display of altruism may make some people scoff given the allegations of sexual misconduct that forced him to take a leave of absence last year from both Hyperloop One and his VC firm Sherpa Capital. Pishevar was arrested last May for alleged rape–not to mention multiple women also stepped forward with past incidents of harassment and misconduct. Pishevar has denied all allegations but dropped his defamation lawsuit against a GOP opposition research firm in February.
Pishevar’s “helping” movement very well may be a PR move or a genuine act of giving or both. Either way, he’s still taking requests.